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Neuroinflammation & Cognition

When the brain is inflamed, thinking suffers.

Understanding it

Inflammation reaches the brain

Chronic inflammation doesn't stop at the neck. When it reaches the brain, it can blunt memory, slow processing and dull mood, often long before anything shows up as a formal diagnosis.

  • Memory lapses or word-finding difficulty
  • Slowed thinking or reduced mental sharpness
  • Mood changes that track with illness or flare-ups
  • Sensitivity to stress, poor sleep or infections
Neuroinflammation & Cognition

Inflammation and the brain

Inflammation is the immune systemโ€™s response to injury, infection and stress. When it becomes chronic and low-grade, research suggests it can affect the brain, contributing to fatigue, low motivation, slowed thinking and low mood in some people. Chronic inflammation is linked with factors such as poor sleep, excess abdominal weight, insulin resistance, smoking, inactivity, ongoing stress and certain medical conditions. This is an evolving area of science, and we are careful to separate what is well established from what is still being studied.

Symptoms people describe

  • Brain fog and slowed thinking
  • Forgetfulness and difficulty concentrating
  • Fatigue and low motivation
  • Low mood that has not responded fully to treatment
  • Symptoms that began after an infection or illness

New or rapidly worsening memory problems, confusion or neurological symptoms need prompt medical and neurological assessment.

Our approach

Assessment

We review medical history, sleep, diet, weight, activity, stress, medications and mood, and check relevant markers such as blood sugar, lipids, thyroid function, vitamin B12, vitamin D and general inflammatory markers where appropriate. We coordinate with your primary care provider or specialists when further workup is needed. See lab testing for mental health.

Addressing well-established drivers

  • Improving sleep and treating sleep apnea where present; see sleep and insomnia
  • Regular physical activity, one of the most consistently supported tools for both mood and cognition
  • A whole-food, Mediterranean-style eating pattern; see nutritional psychiatry
  • Blood sugar and metabolic health
  • Stress reduction and treating depression and anxiety; see inflammation and depression
  • Correcting nutrient deficiencies

Tracking progress

We use questionnaires and simple measures of energy, mood and concentration to see whether changes are helping.

Our providers are licensed naturopathic physicians and mental health counselors led by Dr. Koichi Tanji, ND, LMHC. In Washington, controlled substances such as ADHD stimulants and benzodiazepines are outside naturopathic prescribing scope, so when one is part of the right plan we coordinate with your prescribing physician or nurse practitioner.

Related reading: fatigue and brain fog and functional psychiatry and root causes.

Getting started

We see patients in person at 2135 112th Ave NE, Suite 201, Bellevue, and by secure telehealth anywhere in Washington. We are in-network with Premera, Regence, BlueCross BlueShield, Aetna, Cigna and Kaiser PPO. Most people begin with our Biopsych Assessment. Book online or call (425) 278-6166.

If you are in crisis or thinking about harming yourself, call or text 988 (Suicide & Crisis Lifeline) or call 911.

Our integrated, whole-person approach
How we help

We look for the biological drivers

Through advanced testing, immune reactivity, fatty-acid and plasmalogen status, organic acids and genomics, we map the inflammatory and nutritional factors affecting your brain, then build a plan to calm and restore.

  • Immune, nutrient and cellular-membrane assessment
  • Cellular restoration and precision supplementation
  • Psychotherapy integrated with the medical picture
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Good to know

Frequently asked questions

Can inflammation affect mood and thinking?

Research suggests chronic low-grade inflammation may contribute to fatigue, low motivation, slowed thinking and low mood in some people. It is an active area of research rather than a settled explanation for everyone.

What reduces chronic inflammation?

The best-supported steps are regular physical activity, good sleep, a whole-food Mediterranean-style diet, healthy weight and blood sugar, not smoking and managing stress.

When should memory problems be checked urgently?

Seek prompt medical care for sudden or rapidly worsening memory loss, confusion, speech changes, weakness or other new neurological symptoms.

Is this available by telehealth?

Yes, anywhere in Washington, as well as in person in Bellevue.

Begin with how you're feeling

Care at Sphosh Health starts by understanding the whole context, psychological, biological and behavioral.

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Sphosh Health provides integrated mental health care. Content on this site is for educational purposes and is not a substitute for professional diagnosis or treatment. If you are experiencing a medical or mental health emergency, call 911 or 988 (Suicide & Crisis Lifeline).